Family of structurally-related cell-surface receptors that signal through an intrinsic protein-tyrosine kinase.
Sinônimos
Examples for "erbb receptors"
Examples for "erbb receptors"
1Conversely, inactivation of the ErbB receptors reduces the expression levels of Survivin.
2Several recent evidences suggest that NRG1 and their ErbB receptors are involved in ALS.
3Therefore, our results do not support a role for ErbB receptors as auto-antigens in iMG patients.
4Distributions of ErbB receptors on membranes of SKBR3 breast cancer cells were mapped by immunoelectron microscopy.
5ErbB receptors not only function in cancer, but are also key developmental regulators in the nervous system.
1Conversely, inactivation of the ErbB receptors reduces the expression levels of Survivin.
2Several recent evidences suggest that NRG1 and their ErbB receptors are involved in ALS.
3Therefore, our results do not support a role for ErbB receptors as auto-antigens in iMG patients.
4We describe a new approach that directs ErbB receptor interactions, resulting in biased signaling and phenotypes.
5Activation of ErbB receptor and downstream signaling molecules were observed in neurites only after heregulin stimulation.
1There was also a negative correlation between c-erbB-2 expression and tumor stage.
2Conversely, inactivation of the ErbB receptors reduces the expression levels of Survivin.
3This study revealed that erbB-3 expression was associated with better prognosis.
4Several recent evidences suggest that NRG1 and their ErbB receptors are involved in ALS.
5The only cases showing c-erbB-2 amplification were the two CAexPA cases with high-level immunoreactivity.
6Drug-related interstitial pneumonitis or cardiac dysfunction associated with other ErbB-targeted therapies was not reported.
7These ErbB-2 isoforms function in the nucleus as transcription factors.
8Importantly, we demonstrate that ERBB family mutant cancers are sensitive to treatment with PI3K inhibitors.
9We review here the current understanding of ErbB signaling and DNA double strand break repair.
10Therefore, our results do not support a role for ErbB receptors as auto-antigens in iMG patients.
11Specifically targeting NRG1-ErbB signalling may therefore provide a new therapeutic intervention for relieving incision-induced mechanical allodynia.
12We describe a new approach that directs ErbB receptor interactions, resulting in biased signaling and phenotypes.
13In addition, differential polymerase chain reaction was used to evaluate c-erbB-2 gene amplification in these tumors.
14Activation of ErbB receptor and downstream signaling molecules were observed in neurites only after heregulin stimulation.
15Distributions of ErbB receptors on membranes of SKBR3 breast cancer cells were mapped by immunoelectron microscopy.
16However, further knowledge is still needed to clarify the role of the NRG1-ErbB pathway on MN survival.
Erbb nas variantes da língua
Estados Unidos da América